Where is ghrelin produced?

Where is ghrelin produced?

• A. Stomach
• B. Pancreas
• C. Liver
• D. Adipose tissue

Answer: (A)

Ghrelin is a hunger-stimulating hormone that is produced mainly by the stomach, specifically by X/A-like cells in the fundic mucosa. It rises before meals to signal hunger to the hypothalamus and then falls after eating, helping regulate short‑term appetite and energy balance. While smaller amounts can be produced elsewhere, the stomach is the primary source, making it the best answer. For contrast, the pancreas mainly releases insulin and glucagon, the liver handles many metabolic and synthetic roles, and adipose tissue releases leptin and other adipokines—so ghrelin’s main production site isn’t those tissues.

Ghrelin is a hunger-stimulating hormone that is produced mainly by the stomach, specifically by X/A-like cells in the fundic mucosa. It rises before meals to signal hunger to the hypothalamus and then falls after eating, helping regulate short‑term appetite and energy balance. While smaller amounts can be produced elsewhere, the stomach is the primary source, making it the best answer. For contrast, the pancreas mainly releases insulin and glucagon, the liver handles many metabolic and synthetic roles, and adipose tissue releases leptin and other adipokines—so ghrelin’s main production site isn’t those tissues.